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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC4 All Species: 22.73
Human Site: Y644 Identified Species: 45.45
UniProt: Q9UJX5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX5 NP_037499.2 808 92116 Y644 S C L D A Q F Y D D E T V T V
Chimpanzee Pan troglodytes XP_001165326 808 92071 Y644 S C L D A Q F Y D D E T V T V
Rhesus Macaque Macaca mulatta XP_001082716 809 92216 Y645 S C L D A Q F Y D D E T V T V
Dog Lupus familis XP_536270 808 91824 Y644 S C L D A Q F Y D D E T V T V
Cat Felis silvestris
Mouse Mus musculus Q91W96 807 91689 Y644 S C L D A Q F Y D D E T V T V
Rat Rattus norvegicus NP_001100690 807 91758 Y644 S C L D A Q F Y D D E T V T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513880 760 86226 F618 L A L E F G N F M N T T S D N
Chicken Gallus gallus XP_001231777 799 90763 F639 Y S C L D A H F Y D D E T V T
Frog Xenopus laevis NP_001084578 789 89642 F637 Y S C L D A R F Y D E D I I T
Zebra Danio Brachydanio rerio NP_001008589 797 89831 C629 S V D Y S Y S C L D A R F Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393301 694 78535 A552 N D D G L L V A T C D L D H K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203585 714 79653 K572 R E S F T L D K R S E T D H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 97.5 N.A. 93.4 93.6 N.A. 73.8 74.7 70.7 62.2 N.A. N.A. 29.4 N.A. 38.1
Protein Similarity: 100 100 99.5 98.5 N.A. 96.5 96.5 N.A. 83.2 85.1 82.5 77.2 N.A. N.A. 50.6 N.A. 55.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 6.6 13.3 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 20 26.6 20 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 50 17 0 9 0 0 9 0 0 0 0 % A
% Cys: 0 50 17 0 0 0 0 9 0 9 0 0 0 0 0 % C
% Asp: 0 9 17 50 17 0 9 0 50 75 17 9 17 9 9 % D
% Glu: 0 9 0 9 0 0 0 0 0 0 67 9 0 0 0 % E
% Phe: 0 0 0 9 9 0 50 25 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % K
% Leu: 9 0 59 17 9 17 0 0 9 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 9 0 0 9 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 9 0 9 0 0 9 0 0 0 % R
% Ser: 59 17 9 0 9 0 9 0 0 9 0 0 9 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 0 9 67 9 50 17 % T
% Val: 0 9 0 0 0 0 9 0 0 0 0 0 50 9 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 9 0 9 0 50 17 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _